Dr. Valerie Chew is a principal investigator in Translational Immunology Institute (TII) and an assistant professor in Duke-NUS Medical School, Singapore. Her research focuses primarily on understanding the complexity and diversity of the immune context of the tumor microenvironment and its influence on clinical outcome or response to therapy in patients with hepatocellular carcinoma (HCC). Her current work involves high- and multi-dimensional immunophenotyping and immunomonitoring of HCC microenvironment with cutting edge multiplex and single-cell technologies such as Time of Flight Mass Cytometry (CyTOF), single-cell RNA sequencing (scRNA seq) and spatial transcriptomics (ST). This powerful approach allows holistic profiling of immune landscapes and the identification of clinically relevant immune subsets or biomarkers predictive of tumour progression and response to therapy. Her work has gained recognition with multiple grant awards and several high impact publications.